Cooperative activation is critical for the applications of synthetic biology in mammalian cells.In this study, we have developed cooperative transcription factor by fusing oligomerization domain in mammalian cells.Firstly, we demonstrated that two oligomerized domains (CI434 and CI) successfully improved transcription factor cooperativity in bacter
This paper focuses on a modified Multi-Depot Unmanned Aerial Vehicle Routing Problem (MMDUAVRP).Comparing to classic multi-depot vehicle routing problem, our studied problem has no constraints to restrict the depot where the Unmanned Aerial Vehicle (UAV) departs and returns.This work aims to minimize the number of UAVs and total distance traveled b
Abstract Oncolytic adenoviruses (OAds), most of which are based on species C human adenovirus serotype 5 (Ad5) (OAd5), have recently received much attention as potential anticancer agents.High seroprevalence of anti-Ad5 neutralizing antibodies is a major hurdle for Ad5-based gene therapy.However, the impacts of anti-Ad5 neutralizing antibodies on O
Redoy Ranjan,1,2 Dipannita Adhikary,2 Debasish Das,3 Asit Baran Adhikary1 1Department of Cardiac Surgery, Summer Hat Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh; 2Department of Medicine & Veterinary Medicine, The University of Edinburgh, Edinburgh, UK; 3Department of Thoracic Surgery, Dhaka Medical College & Hospital, Dhaka, Bang